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Coronavirus Patent

https://patents.justia.com/patent/10130701

Jul 23, 2015 – THE PIRBRIGHT INSTITUTE

The present invention provides a live, attenuated coronavirus comprising a variant replicase gene encoding polyproteins comprising a mutation in one or more of non-structural protein(s) (nsp)-10, nsp-14, nsp-15 or nsp-16. The coronavirus may be used as a vaccine for treating and/or preventing a disease, such as infectious bronchitis, in a subject.


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